Inaccuracy of a “Spiked Curve” for Monitoring Unfractionated Heparin Therapy
نویسندگان
چکیده
منابع مشابه
Establishing the heparin therapeutic range using aPTT and anti-Xa measurements for monitoring unfractionated heparin therapy
BACKGROUND Unfractionated heparin (UFH) has unstable pharmacokinetics and requires close monitoring. The activated partial thromboplastin time (aPTT) test has been used to monitor UFH therapy for decades in Korea, but its results can be affected by numerous variables. We established an aPTT heparin therapeutic range (HTR) corresponding to therapeutic anti-Xa levels for continuous intravenous UF...
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چکیده ندارد.
15 صفحه اولMonitoring unfractionated heparin with the aPTT: time for a fresh look.
Laboratory monitoring is widely recommended to measure the anticoagulant effect of unfractionated heparin and to adjust the dose to maintain levels in the target therapeutic range. The most widely used laboratory assay for monitoring unfractionated heparin therapy is the activated partial thromboplastin time (aPTT). A fixed therapeutic range for the aPTT of 1.5 to 2.5 times the control value ha...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2011
ISSN: 0002-9173,1943-7722
DOI: 10.1309/ajcp60zgxcjkrmjo